HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

David Pleasure Selected Research

aspartoacylase

11/2021Ablating the Transporter Sodium-Dependent Dicarboxylate Transporter 3 Prevents Leukodystrophy in Canavan Disease Mice.
1/2020Antisense Oligonucleotide Reverses Leukodystrophy in Canavan Disease Mice.
1/2018Brain Nat8l Knockdown Suppresses Spongiform Leukodystrophy in an Aspartoacylase-Deficient Canavan Disease Mouse Model.
11/2017Suppressing N-Acetyl-l-Aspartate Synthesis Prevents Loss of Neurons in a Murine Model of Canavan Leukodystrophy.
5/2015Ablating N-acetylaspartate prevents leukodystrophy in a Canavan disease model.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown:


David Pleasure Research Topics

Disease

10Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
12/2021 - 01/2007
9Multiple Sclerosis
01/2022 - 01/2007
8Demyelinating Diseases (Demyelinating Disease)
01/2017 - 08/2007
5Canavan Disease (Leukodystrophy, Spongiform)
11/2021 - 05/2015
3Central Nervous System Diseases (CNS Diseases)
01/2012 - 10/2002
3Ischemia
08/2008 - 10/2002
2Ataxia (Dyssynergia)
11/2021 - 01/2020
2Atrophy
01/2020 - 11/2017
2Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy)
01/2016 - 03/2005
2Gliosis
10/2013 - 01/2008
2Hypoxia (Hypoxemia)
08/2011 - 02/2002
2Brain Ischemia (Cerebral Ischemia)
05/2008 - 10/2002
2Inflammation (Inflammations)
01/2008 - 01/2007
2Necrosis
03/2003 - 10/2002
1Disease Progression
12/2021
1Paralysis (Palsy)
01/2012
1Relapsing-Remitting Multiple Sclerosis
11/2011
1Neuromuscular Diseases (Neuromuscular Disease)
04/2011
1Microcephaly
12/2010
1Neuroblastoma
04/2010
1Mitochondrial Diseases (Mitochondrial Disease)
03/2010
1Pain (Aches)
08/2008
1Partial Epilepsies (Epilepsy, Partial)
05/2008
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
05/2008
1Infarction (Infarctions)
05/2008
1Neurologic Manifestations (Neurological Manifestations)
05/2008
1Olivopontocerebellar Atrophies (Olivopontocerebellar Atrophy)
05/2008
1Brain Diseases (Brain Disorder)
05/2008
1Encephalitis (Encephalitis, Rasmussen)
05/2008
1Transient Ischemic Attack
05/2008
1Spinal Muscular Atrophy (Progressive Muscular Atrophy)
03/2005
1Inborn Genetic Diseases (Disease, Hereditary)
03/2005
1Fabry Disease (Fabry's Disease)
03/2005
1Wallerian Degeneration
10/2003
1Fasciculation (Fasciculations)
10/2003
1Crush Injuries
10/2003
1Acidosis
03/2003
1Teratocarcinoma
02/2002

Drug/Important Bio-Agent (IBA)

9Peptides (Polypeptides)IBA
06/2014 - 01/2007
9Myelin-Oligodendrocyte GlycoproteinIBA
06/2014 - 01/2007
5aspartoacylaseIBA
11/2021 - 05/2015
4N-acetylaspartate (N-acetyl aspartate)IBA
11/2021 - 05/2015
3EnzymesIBA
01/2020 - 03/2005
3Glutamate Receptors (Glutamate Receptor)IBA
01/2012 - 10/2002
3Proteins (Proteins, Gene)FDA Link
01/2012 - 03/2005
2Interferon-gamma (Interferon, gamma)IBA
01/2012 - 11/2011
2NestinIBA
08/2011 - 12/2010
2Glial Fibrillary Acidic ProteinIBA
08/2011 - 01/2007
2Messenger RNA (mRNA)IBA
08/2011 - 10/2003
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2011 - 10/2003
2AcidsIBA
08/2008 - 10/2002
2Glucose (Dextrose)FDA LinkGeneric
03/2003 - 02/2002
2Oxygen (Dioxygen)IBA
03/2003 - 02/2002
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
01/2022
1myelin oligodendrocyte glycoprotein (35-55)IBA
12/2021
1SodiumIBA
11/2021
1Dicarboxylic Acid TransportersIBA
11/2021
1locked nucleic acidIBA
01/2020
1Antisense OligonucleotidesIBA
01/2020
1AcetyltransferasesIBA
01/2018
1RNA (Ribonucleic Acid)IBA
01/2018
1ChemokinesIBA
06/2014
1peptide AIBA
06/2014
1CuprizoneIBA
09/2012
1Lysophosphatidylcholines (Lysophosphatidylcholine)IBA
08/2012
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
01/2012
1N-Methylaspartate (NMDA)IBA
01/2012
1Interferon-betaIBA
11/2011
1Proteoglycans (Proteoglycan)IBA
11/2011
1VimentinIBA
08/2011
1NucleotidesIBA
04/2011
1InterferonsIBA
01/2011
1Conditioned Culture MediaIBA
04/2010
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
04/2010
1Cyclic AMP (AMP, Cyclic)IBA
04/2010
1Mitochondrial DNA (mtDNA)IBA
03/2010
1Acid Sensing Ion ChannelsIBA
08/2008
1AutoantibodiesIBA
05/2008
1Biomarkers (Surrogate Marker)IBA
05/2008
1Myelin ProteinsIBA
01/2008
1Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
01/2008
1AMPA Receptors (AMPA Receptor)IBA
08/2007
1Fatty Acid-Binding Protein 7IBA
01/2007
1alpha-Galactosidase (Beano)IBA
03/2005
1Ascorbic Acid (Vitamin C)FDA LinkGeneric
03/2005
1LigandsIBA
10/2003
1NeuropilinsIBA
10/2003
1Semaphorin-3AIBA
10/2003
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2002
1Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA
10/2002
1NF-kappa B (NF-kB)IBA
10/2002
1Kainic Acid (Kainate)IBA
10/2002
1alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA
10/2002
16- hydroxy- 2,5,7,8- tetramethylchroman- 2- carboxylic acid (Trolox)IBA
02/2002
1Free RadicalsIBA
02/2002
1Rutin (Rutoside)IBA
02/2002
1Pharmaceutical PreparationsIBA
02/2002

Therapy/Procedure

4Therapeutics
01/2017 - 03/2005
1Cell Transplantation
01/2017
1Precision Medicine
01/2016